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AU launches Consortium for COVID-19 Vaccine Clinical Trial

The African Union Commission has launched the Africa Centres for Disease Control and Prevention (Africa CDC) Consortium for COVID-19 Vaccine Clinical Trial (CONCVACT).

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CONCVACT is being implemented as part of the Africa Joint Continental Strategy for COVID-19 endorsed by African Ministers of Health on 22 February 2020 in Addis Ababa, Ethiopia, and approved by the Bureau of the Assembly of African Union Heads of State and Government on 26 March 2020.

Driven by the principles of cooperation, coordination, collaboration and communication, the strategy aims to prevent severe illness and deaths due to COVID-19 infection in African Union Member States, minimize social disruption, and mitigate the economic consequences of COVID-19.

“Success in developing and providing access to a safe vaccine requires an innovative and collaborative approach, with significant local manufacturing in Africa. We need to support the contribution of African scientists and healthcare professionals. We need to act with urgency,” said H.E. President Cyril Ramaphosa.

Rolling out a vaccine in Africa is key to achieving all the three pillars of the Africa Joint Continental Strategy for COVID-19: limiting transmission, preventing deaths and laying the foundation for socio-economic recovery that should bring Africa’s integration agenda back on track.

“It is critically important for academics, researchers and the private sector to work together and use all available platforms for the development of COVID-19 vaccine, which will enable Africa to regain momentum for achieving the goals of the continental integration agenda,” said H.E. Moussa Faki Mahamat, Chairperson of the African Union Commission.

CONCVACT aims to secure more than 10 late stage vaccine clinical trials as early as possible on the continent by bringing together global vaccine developers and funders, as well as African organizations that facilitate clinical trials. The goal is to ensure that sufficient data is generated on the safety and efficacy of the most promising vaccine candidates for the African population so they can be confidently rolled out in Africa once vaccines are approved.

“There is urgent need for global solidarity, cooperation, and appropriate regulation to ensure equitable access to potential COVID-19 vaccine. The African Union will continue to partner with GAVI, WHO and other relevant stakeholders in the development of COVID-19 vaccine,” said H.E. Amira Elfadil Mohammed, Commissioner for Social Affairs, African Union Commission.

CONCVACT will be co-chaired by Dr Salim Abdool Karim, Head of the Ministerial Advisory Committee for COVID-19 in South Africa; Dr Samba Sow, Director-General, Center for Vaccine Development of Mali; and Dr John Nkengasong, Director of Africa CDC. Other members of the consortium will include representatives of key organizations supporting clinical trials on the continent, including the WHO, The Africa Academy of Sciences’ Clinical Trials Community, Institute Pasteur, African Vaccine Regulatory Forum, African Medicines Agency, NEPAD, and others.

“The African initiative to develop a vaccine against the new coronavirus is welcomed and encouraged. Through this initiative, Africa will be at the forefront as the world seeks to overcome the COVID-19 pandemic,” said Prof. Moustafa Mijiyawa, Chair of the Africa CDC Governing Board and Minister of Health of Togo.

Africa CDC will embark on a multi-stakeholder partnerships drive to advance CONCVACT and other subsidiary initiatives, to ensure broad endorsement and support across Africa, by institutions and the African people. “Africa must play an active role in securing an effective vaccine against COVID-19. This is about our future and our development,” said Dr John Nkengasong.

 

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